Mammals evolved divergent architectures of placenta to receive nourishment from the mother during embryogenesis.
In our lab, we seek to understand how the uterine microenvironment shapes the fetal-placental interface of various animals, by using early embryos and placental organoids.
Our ultimate goal is to investigate how complex and diverse structures emerge to achieve similar functions.
Comparative early embryology: we aim to uncover the processes governing cell fate decisions in embryos a few days after fertilization.
Interorganismal fetal-maternal interface: we aim to reproduce the fetal-maternal interface in vitro to study the principles that make pregnancy possible.
Evolutionary morphogenesis: we want to understand the mechanisms that led to the evolution of striking different placenta shapes.
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