{"id":19,"date":"2023-01-27T15:12:48","date_gmt":"2023-01-27T15:12:48","guid":{"rendered":"https:\/\/development.gerrilab.org\/?page_id=19"},"modified":"2024-09-20T12:22:20","modified_gmt":"2024-09-20T12:22:20","slug":"research","status":"publish","type":"page","link":"https:\/\/gerrilab.org\/?page_id=19","title":{"rendered":"Research"},"content":{"rendered":"\n<div class=\"wp-block-cover alignfull is-light\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-white-background-color has-background-dim-100 has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<p class=\"has-text-align-center has-large-font-size\"><strong>Comparative early embryology<\/strong><\/p>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p style=\"font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.354), 18px);\">Mammalian early embryos share multiple features, and early developmental processes are widely regarded as highly conserved. However, major cell specification events are species-specific. In this branch of the lab, we aim to uncover what are the shared and unique molecular and cellular processes that govern cell fate decisions across species.<\/p>\n\n\n\n<div style=\"height:80px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-cover alignfull is-light\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-100 has-background-dim\" style=\"background-color:#e5e9ec\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-align-center has-large-font-size\"><strong>Interorganismal fetal-maternal interface<\/strong><\/p>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\">\n<p style=\"font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.354), 18px);\">The intimate interaction between the developing embryo and the uterine microenvironment is central for a successful pregnancy. This dynamic crosstalk does not only shape the embryo proper, but it is essential for the health of the mother. Here, we study how this elegant interface between two organisms is established and regulated.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image alignright size-large\"><a href=\"https:\/\/gerrilab.org\/wp-content\/uploads\/2024\/01\/Implantation_030124_FINAL.png\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"964\" src=\"https:\/\/gerrilab.org\/wp-content\/uploads\/2024\/01\/Implantation_030124_FINAL-1024x964.png\" alt=\"\" class=\"wp-image-789\" srcset=\"https:\/\/gerrilab.org\/wp-content\/uploads\/2024\/01\/Implantation_030124_FINAL-1024x964.png 1024w, https:\/\/gerrilab.org\/wp-content\/uploads\/2024\/01\/Implantation_030124_FINAL-300x282.png 300w, https:\/\/gerrilab.org\/wp-content\/uploads\/2024\/01\/Implantation_030124_FINAL-768x723.png 768w, https:\/\/gerrilab.org\/wp-content\/uploads\/2024\/01\/Implantation_030124_FINAL-1536x1446.png 1536w, https:\/\/gerrilab.org\/wp-content\/uploads\/2024\/01\/Implantation_030124_FINAL-2048x1928.png 2048w, https:\/\/gerrilab.org\/wp-content\/uploads\/2024\/01\/Implantation_030124_FINAL-2000x1883.png 2000w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption class=\"wp-element-caption\">\u00a9 Michaela Burkon, powered by Biorender<\/figcaption><\/figure>\n\n\n\n<p class=\"has-text-align-right\" style=\"font-size:12px\"><\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:80px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-cover alignfull is-light\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-cyan-bluish-gray-background-color has-background-dim-100 has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-align-center has-large-font-size\"><strong>Evolutionary morphogenesis<\/strong><\/p>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\">\n<p style=\"font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.354), 18px);\">The placenta is an essential organ for the success of mammalian reproduction. Even though the internal organs are structurally similar in the early embryonic stages across mammals, the placenta evolved strikingly different architectures. By taking an evolutionary approach, we aim to understand the mechanisms underlying how placenta became different from a morphological point of view, while retaining a similar function across species.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image alignright size-large\"><a href=\"https:\/\/gerrilab.org\/wp-content\/uploads\/2024\/09\/placenta-overview-species_cat.png\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"583\" src=\"https:\/\/gerrilab.org\/wp-content\/uploads\/2024\/09\/placenta-overview-species_cat-1024x583.png\" alt=\"\" class=\"wp-image-871\" srcset=\"https:\/\/gerrilab.org\/wp-content\/uploads\/2024\/09\/placenta-overview-species_cat-1024x583.png 1024w, https:\/\/gerrilab.org\/wp-content\/uploads\/2024\/09\/placenta-overview-species_cat-300x171.png 300w, https:\/\/gerrilab.org\/wp-content\/uploads\/2024\/09\/placenta-overview-species_cat-2000x1139.png 2000w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption class=\"wp-element-caption\">\u00a9 Michaela Burkon, powered by Biorender<\/figcaption><\/figure>\n\n\n\n<p class=\"has-text-align-right\" style=\"font-size:12px\"><\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:80px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/div>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":69,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inspiro_hide_title":false,"footnotes":""},"class_list":["post-19","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/gerrilab.org\/index.php?rest_route=\/wp\/v2\/pages\/19","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gerrilab.org\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/gerrilab.org\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/gerrilab.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/gerrilab.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=19"}],"version-history":[{"count":54,"href":"https:\/\/gerrilab.org\/index.php?rest_route=\/wp\/v2\/pages\/19\/revisions"}],"predecessor-version":[{"id":879,"href":"https:\/\/gerrilab.org\/index.php?rest_route=\/wp\/v2\/pages\/19\/revisions\/879"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gerrilab.org\/index.php?rest_route=\/wp\/v2\/media\/69"}],"wp:attachment":[{"href":"https:\/\/gerrilab.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=19"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}